The FANCL antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to FANCL. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The FANCL antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth